In Hitfilm, I render my videos using "Youtube 1080p HD MP4 1920x1080"
For example, the last project ended up rendering to 6.2GB in size.
My internet is not so fast, so uploading 6+GB files takes a very long time.
So I ran the 6.2GB file through Handbrake using "Very Fast 1080p30", and the file ended up being the exact same resolution and ended up being 480MB, and I cannot notice any loss of quality.
So 480MB is a lot faster and easier for me to upload to youtube:)
Hope this is useful to others, or maybe there is a better way achieving this in Hitfilm?